Taken together, through rigorous testing and validation, we demonstrate that our effective droplet model is a pragmatic, fast and a computationally efficient option, if simulations of phase separated droplets in large-scale emulsions are desired. Furthermore, we also show that our model accurately captures the dynamic out of equilibrium behaviour of droplets in the presence of chemical reactions and external chemical gradients. We then demonstrate that our choice of the optimum parameters indeed leads to faithful capturing of droplet dynamics in emulsions across a multitude of situations ranging from a single droplet in a large system to coarsening behaviour of 100 thousand droplets. In the second part of the thesis, we choose optimum values for the simulation parameters in the effective droplet model using a synthetic test-case and comparing it with the ground truth, i.e., simulations using the Cahn-Hilliard model. The effective droplet model has many simulation parameters which need to be carefully chosen to faithfully capture growth and drift of droplets. These fluxes also affect the dynamics of the dilute phase itself. The dynamics of droplet growth and drift follows from material fluxes exchanged between the droplet and the dilute phase, which are obtained from solving a steady-state reaction-diffusion equation inside all sectors. We then study interaction of the droplets with the dilute phase by discretizing their vicinity into thin annular sectors. Droplets are then well described by their positions and radii, and the dilute phase dynamics by a coarse reaction-diffusion equation. To this end, we consider a typical situation of many spherical droplets formed via Liquid-liquid phase separation and are far away from each other. In such an effective droplet model, we replace the description of the full volume fraction field stemming from the Cahn-Hilliard model with pertinent degrees of freedom for the phase separated droplets. In the first part of the thesis, we derive observations from typical simulations of the Cahn-Hilliard model, and build the theory for an effective droplet model with reasonable analytical assumptions. The aim of this thesis was to disentangle and model the effects of chemical reactions and external chemical gradients on the dynamics of such phase separated droplets via numerical simulations, and thus gain insights on how cell regulates the dynamics, formation, dissolution and stability of it's condensates. In this thesis, we will develop a fast and efficient numerical model for simulating dynamics of droplets which have been phase separated from a dilute phase, without solving the computationally expensive Cahn-Hilliard equation that describes phase separation. The cell exercises this control through various mechanisms, two of them being chemical reactions and external chemical gradients. Precise spatiotemporal regulation of condensates is essential for proper functioning of the cell and its survival. This phenomena has been observed in biological cells as well, where membrane-less organelles, also known as condensates, form in the cell through Liquid-liquid phase separation. English Liquid-liquid phase separation is ubiquitous in everyday life, such as formation of oil droplets in water.
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